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Early Effects of the Soluble Amyloid β(25-35) Peptide in Rat Cortical Neurons: Modulation of Signal Transduction Mediated by Adenosine and Group I Metabotropic Glutamate Receptors

The amyloid β peptide (Aβ) is a central player in the neuropathology of Alzheimer’s disease (AD). The alteration of Aβ homeostasis may impact the fine-tuning of cell signaling from the very beginning of the disease, when amyloid plaque is not deposited yet. For this reason, primary culture of rat co...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Castillo, Carlos Alberto, Ballesteros-Yáñez, Inmaculada, León-Navarro, David Agustín, Albasanz, José Luis, Martín, Mairena
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8234864/
https://ncbi.nlm.nih.gov/pubmed/34205261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22126577
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