Complement Components C3 and C4 Indicate Vasculitis Manifestations to Distinct Renal Compartments in ANCA-Associated Glomerulonephritis

Acute kidney injury (AKI) is a common and severe complication of antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) causing progressive chronic kidney disease (CKD), end-stage renal disease (ESRD) or death. Pathogenic ANCAs, in particular proteinase 3 (PR3) and myeloperoxidase...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Hakroush, Samy, Tampe, Désirée, Korsten, Peter, Ströbel, Philipp, Tampe, Björn
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8234841/
https://ncbi.nlm.nih.gov/pubmed/34205415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22126588
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