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Immune Cell Modulation of the Extracellular Matrix Contributes to the Pathogenesis of Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy with a five-year survival rate of only 9%. PDAC is characterized by a dense, fibrotic stroma composed of extracellular matrix (ECM) proteins. This desmoplastic stroma is a hallmark of PDAC, representing a significant physical barr...

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Dettagli Bibliografici
Pubblicato in:Biomolecules
Autori principali: Ahmad, Ramiz S., Eubank, Timothy D., Lukomski, Slawomir, Boone, Brian A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8234537/
https://ncbi.nlm.nih.gov/pubmed/34204306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11060901
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