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Kras activation in endometrial organoids drives cellular transformation and epithelial-mesenchymal transition
KRAS, an oncogene, is frequently activated by mutations in many cancers. Kras-driven adenocarcinoma development in the lung, pancreas, and biliary tract has been extensively studied using gene targeting in mice. By taking the organoid- and allograft-based genetic approach to these organs, essentiall...
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| Publicado en: | Oncogenesis |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8233399/ https://ncbi.nlm.nih.gov/pubmed/34172714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-021-00337-8 |
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