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Light-driven decarboxylative deuteration enabled by a divergently engineered photodecarboxylase
Despite the well-established chemical processes for C-D bond formation, the toolbox of enzymatic methodologies for deuterium incorporation has remained underdeveloped. Here we describe a photodecarboxylase from Chlorella variabilis NC64A (CvFAP)-catalyzed approach for the decarboxylative deuteration...
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| Udgivet i: | Nat Commun |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8233396/ https://ncbi.nlm.nih.gov/pubmed/34172745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24259-6 |
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