Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders

Cellular heterogeneity in the human brain obscures the identification of robust cellular regulatory networks, which is necessary to understand the function of non-coding elements and the impact of non-coding genetic variation. Here we integrate genome-wide chromosome conformation data from purified...

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Udgivet i:Nat Commun
Main Authors: Hu, Benxia, Won, Hyejung, Mah, Won, Park, Royce B., Kassim, Bibi, Spiess, Keeley, Kozlenkov, Alexey, Crowley, Cheynna A., Pochareddy, Sirisha, Li, Yun, Dracheva, Stella, Sestan, Nenad, Akbarian, Schahram, Geschwind, Daniel H.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8233376/
https://ncbi.nlm.nih.gov/pubmed/34172755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24243-0
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