HP1α is a chromatin crosslinker that controls nuclear and mitotic chromosome mechanics

Chromatin, which consists of DNA and associated proteins, contains genetic information and is a mechanical component of the nucleus. Heterochromatic histone methylation controls nucleus and chromosome stiffness, but the contribution of heterochromatin protein HP1α (CBX5) is unknown. We used a novel...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Strom, Amy R, Biggs, Ronald J, Banigan, Edward J, Wang, Xiaotao, Chiu, Katherine, Herman, Cameron, Collado, Jimena, Yue, Feng, Ritland Politz, Joan C, Tait, Leah J, Scalzo, David, Telling, Agnes, Groudine, Mark, Brangwynne, Clifford P, Marko, John F, Stephens, Andrew D
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2021
Assuntos:
Cell Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8233041/
https://ncbi.nlm.nih.gov/pubmed/34106828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.63972
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