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Lysine methylation shields an intracellular pathogen from ubiquitylation and autophagy

Many intracellular pathogens avoid detection by their host cells. However, it remains unknown how they avoid being tagged by ubiquitin, an initial step leading to antimicrobial autophagy. Here, we show that the intracellular bacterial pathogen Rickettsia parkeri uses two protein-lysine methyltransfe...

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Detalles Bibliográficos
Publicado en:Sci Adv
Main Authors: Engström, Patrik, Burke, Thomas P., Tran, Cuong J., Iavarone, Anthony T., Welch, Matthew D.
Formato: Artigo
Idioma:Inglês
Publicado: American Association for the Advancement of Science 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8232902/
https://ncbi.nlm.nih.gov/pubmed/34172444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abg2517
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