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Metabolism of 2,3-Dehydrosilybin A and 2,3-Dehydrosilybin B: A Study with Human Hepatocytes and Recombinant UDP-Glucuronosyltransferases and Sulfotransferases

2,3-Dehydrosilybin A and 2,3-dehydrosilybin B are a pair of enantiomers formed by the oxidation of the natural flavonolignans silybin A and silybin B, respectively. However, the antioxidant activity of 2,3-dehydrosilybin molecules is much stronger than that of their precursors. Here, we investigated...

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Bibliographic Details
Published in:Antioxidants (Basel)
Main Authors: Vrba, Jiří, Papoušková, Barbora, Lněničková, Kateřina, Kosina, Pavel, Křen, Vladimír, Ulrichová, Jitka
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8232340/
https://ncbi.nlm.nih.gov/pubmed/34198653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox10060954
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