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A Mathematical Description of the Bone Marrow Dynamics during CAR T-Cell Therapy in B-Cell Childhood Acute Lymphoblastic Leukemia

Chimeric Antigen Receptor (CAR) T-cell therapy has demonstrated high rates of response in recurrent B-cell Acute Lymphoblastic Leukemia in children and young adults. Despite this success, a fraction of patients’ experience relapse after treatment. Relapse is often preceded by recovery of healthy B c...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Martínez-Rubio, Álvaro, Chulián, Salvador, Blázquez Goñi, Cristina, Ramírez Orellana, Manuel, Pérez Martínez, Antonio, Navarro-Zapata, Alfonso, Ferreras, Cristina, Pérez-García, Victor M., Rosa, María
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8232108/
https://ncbi.nlm.nih.gov/pubmed/34198713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22126371
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