The Serpin Superfamily and Their Role in the Regulation and Dysfunction of Serine Protease Activity in COPD and Other Chronic Lung Diseases

Chronic obstructive pulmonary disease (COPD) is a debilitating heterogeneous disease characterised by unregulated proteolytic destruction of lung tissue mediated via a protease-antiprotease imbalance. In COPD, the relationship between the neutrophil serine protease, neutrophil elastase, and its endo...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kelly-Robinson, Gillian A., Reihill, James A., Lundy, Fionnuala T., McGarvey, Lorcan P., Lockhart, John C., Litherland, Gary J., Thornbury, Keith D., Martin, S. Lorraine
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8231800/
https://ncbi.nlm.nih.gov/pubmed/34198546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22126351
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