NRG-HN003: Phase I and Expansion Cohort Study of Adjuvant Pembrolizumab, Cisplatin and Radiation Therapy in Pathologically High-Risk Head and Neck Cancer

SIMPLE SUMMARY: The anti-PD1 monoclonal antibody pembrolizumab improves survival in recurrent/metastatic head and neck squamous cell carcinoma. Patients with locoregional, pathologically high-risk disease recur frequently despite adjuvant cisplatin–radiation therapy. Targeting PD1 may reverse immuno...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Bauman, Julie E., Harris, Jonathan, Uppaluri, Ravindra, Yao, Min, Ferris, Robert L., Chen, Josephine, Jordan, Richard C., Joshi, Nikhil P., Jujjuvaparu, Srinivas, Blakaj, Dukagjin M., Henson, Christina, Sheqwara, Jawad, Mell, Loren K., Sen, Neilayan, Clump, David A., Garg, Madhur K., Yilmaz, Emrullah, Torres-Saavedra, Pedro, Le, Quynh-Thu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8230356/
https://ncbi.nlm.nih.gov/pubmed/34207599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13122882
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