Improving the Pharmacological Properties of Ciclopirox for Its Use in Congenital Erythropoietic Porphyria

Congenital erythropoietic porphyria (CEP), also known as Günther’s disease, results from a deficient activity in the fourth enzyme, uroporphyrinogen III synthase (UROIIIS), of the heme pathway. Ciclopirox (CPX) is an off-label drug, topically prescribed as an antifungal. It has been recently shown t...

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Bibliographic Details
Published in:J Pers Med
Main Authors: Bernardo-Seisdedos, Ganeko, Charco, Jorge M., SanJuan, Itxaso, García-Martínez, Sandra, Urquiza, Pedro, Eraña, Hasier, Castilla, Joaquín, Millet, Oscar
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8230281/
https://ncbi.nlm.nih.gov/pubmed/34071291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jpm11060485
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