A Rational Designed Novel Bispecific Antibody for the Treatment of GBM

Epidermal growth factor receptor variant III (EGFRvIII) is highly and specifically expressed in a subset of lethal glioblastoma (GBM), making the receptor a unique therapeutic target for GBM. Recently, bispecific antibodies (BsAbs) have shown exciting clinical benefits in cancer immunotherapy. Here,...

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Pubblicato in:Biomedicines
Autori principali: Sun, Rui, Zhou, Yuexian, Han, Lei, Pan, Zhidi, Chen, Jie, Zong, Huifang, Bian, Yanlin, Jiang, Hua, Zhang, Baohong, Zhu, Jianwei
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8230177/
https://ncbi.nlm.nih.gov/pubmed/34204931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9060640
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