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Discovering Cellular Mitochondrial Heteroplasmy Heterogeneity with Single Cell RNA and ATAC Sequencing

SIMPLE SUMMARY: Mitochondria, the powerhouse of the cell, exist in the range of 100 s–1000 s of copies in almost every cell in the body, each with their own mitochondrial DNA, called mtDNA. When the healthy operation of a significant proportion of these mitochondria is disrupted, it can lead to dysf...

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Detalhes bibliográficos
Publicado no:Biology (Basel)
Main Authors: Marshall, Aidan S., Jones, Nick S.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8230039/
https://ncbi.nlm.nih.gov/pubmed/34198745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology10060503
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