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Discovering Cellular Mitochondrial Heteroplasmy Heterogeneity with Single Cell RNA and ATAC Sequencing

SIMPLE SUMMARY: Mitochondria, the powerhouse of the cell, exist in the range of 100 s–1000 s of copies in almost every cell in the body, each with their own mitochondrial DNA, called mtDNA. When the healthy operation of a significant proportion of these mitochondria is disrupted, it can lead to dysf...

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Vydáno v:Biology (Basel)
Hlavní autoři: Marshall, Aidan S., Jones, Nick S.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8230039/
https://ncbi.nlm.nih.gov/pubmed/34198745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology10060503
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