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Antimicrobial Activity of Quasi-Enantiomeric Cinchona Alkaloid Derivatives and Prediction Model Developed by Machine Learning

Bacterial infections that do not respond to current treatments are increasing, thus there is a need for the development of new antibiotics. Series of 20 N-substituted quaternary salts of cinchonidine (CD) and their quasi-enantiomer cinchonine (CN) were prepared and their antimicrobial activity was a...

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Detalhes bibliográficos
Publicado no:Antibiotics (Basel)
Main Authors: Ramić, Alma, Skočibušić, Mirjana, Odžak, Renata, Čipak Gašparović, Ana, Milković, Lidija, Mikelić, Ana, Sović, Karlo, Primožič, Ines, Hrenar, Tomica
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8229948/
https://ncbi.nlm.nih.gov/pubmed/34073082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics10060659
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