Effect of Coxsackievirus B4 Infection on the Thymus: Elucidating Its Role in the Pathogenesis of Type 1 Diabetes

The thymus gland is a primary lymphoid organ for T-cell development. Various viral infections can result in disturbance of thymic functions. Medullary thymic epithelial cells (mTECs) are important for the negative selection of self-reactive T-cells to ensure central tolerance. Insulin-like growth fa...

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Bibliographische Detailangaben
Veröffentlicht in:Microorganisms
Hauptverfasser: Alhazmi, Abdulaziz, Nekoua, Magloire Pandoua, Michaux, Hélène, Sane, Famara, Halouani, Aymen, Engelmann, Ilka, Alidjinou, Enagnon Kazali, Martens, Henri, Jaidane, Hela, Geenen, Vincent, Hober, Didier
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8229779/
https://ncbi.nlm.nih.gov/pubmed/34072590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/microorganisms9061177
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