Neisseria meningitidis Factor H Binding Protein Surface Exposure on Salmonella Typhimurium GMMA Is Critical to Induce an Effective Immune Response against Both Diseases

GMMA, outer membrane vesicles resulting from hyperblebbing mutated bacterial strains, are a versatile vaccine platform for displaying both homologous and heterologous antigens. Periplasmic expression is a popular technique for protein expression in the lumen of the blebs. However, the ability of int...

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Veröffentlicht in:Pathogens
Hauptverfasser: Necchi, Francesca, Stefanetti, Giuseppe, Alfini, Renzo, Palmieri, Elena, Carducci, Martina, Di Benedetto, Roberta, Schiavo, Fabiola, Aruta, Maria Grazia, Giusti, Fabiola, Ferlenghi, Ilaria, Goh, Yun Shan, Rondini, Simona, Micoli, Francesca
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8229706/
https://ncbi.nlm.nih.gov/pubmed/34207575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pathogens10060726
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