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An Easy Synthesis of Monofluorinated Derivatives of Pyrroles from β-Fluoro-β-Nitrostyrenes

The catalyst-free conjugate addition of pyrroles to β-Fluoro-β-nitrostyrenes was investigated. The reaction was found to proceed under solvent-free conditions to form 2-(2-Fluoro-2-nitro-1-arylethyl)-1H-pyrroles. The effectiveness of this approach was demonstrated through the preparation of a series...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Aldoshin, Alexander S., Tabolin, Andrey A., Ioffe, Sema L., Nenajdenko, Valentine G.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8229656/
https://ncbi.nlm.nih.gov/pubmed/34207692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26123515
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