Analysis of Pembrolizumab in Human Plasma by LC-MS/HRMS. Method Validation and Comparison with Elisa

Pembrolizumab is a humanized immunoglobulin G4-kappa anti-PD1 antibody used in the treatment of different solid tumors or haematological malignancies. A liquid chromatography coupled with a high resolution mass spectrometry (orbitrap technology) method was fully developed, optimized, and validated f...

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Vydáno v:Biomedicines
Hlavní autoři: Millet, Aurélien, Khoudour, Nihel, Guitton, Jérôme, Lebert, Dorothée, Goldwasser, François, Blanchet, Benoit, Machon, Christelle
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8229588/
https://ncbi.nlm.nih.gov/pubmed/34070939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9060621
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