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DNA Methylation of Human Choline Kinase Alpha Promoter-Associated CpG Islands in MCF-7 Cells

Choline kinase (CK) is the enzyme catalyzing the first reaction in CDP-choline pathway for the biosynthesis of phosphatidylcholine. Higher expression of the α isozyme of CK has been implicated in carcinogenesis, and inhibition or downregulation of CKα (CHKA) is a promising anticancer approach. This...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Mohamed Sa’dom, Siti Aisyah Faten, Raikundalia, Sweta, Shamsuddin, Shaharum, See Too, Wei Cun, Few, Ling Ling
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8229565/
https://ncbi.nlm.nih.gov/pubmed/34205960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12060853
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