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The AMPK/p27(Kip1) Pathway as a Novel Target to Promote Autophagy and Resilience in Aged Cells
Once believed to solely function as a cyclin-dependent kinase inhibitor, p27(Kip1) is now emerging as a critical mediator of autophagy, cytoskeletal dynamics, cell migration and apoptosis. During periods of metabolic stress, the subcellular location of p27(Kip1) largely dictates its function. Cytopl...
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| Veröffentlicht in: | Cells |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8229180/ https://ncbi.nlm.nih.gov/pubmed/34201101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10061430 |
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