C4b-binding protein α-chain enhances antitumor immunity by facilitating the accumulation of tumor-infiltrating lymphocytes in the tumor microenvironment in pancreatic cancer

BACKGROUND: Recent studies indicate that complement plays pivotal roles in promoting or suppressing cancer progression. We have previously identified C4b-binding protein α-chain (C4BPA) as a serum biomarker for the early detection of pancreatic ductal adenocarcinoma (PDAC). However, its mechanism of...

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Bibliografiske detaljer
Udgivet i:J Exp Clin Cancer Res
Main Authors: Sasaki, Kosuke, Takano, Shigetsugu, Tomizawa, Satoshi, Miyahara, Yoji, Furukawa, Katsunori, Takayashiki, Tsukasa, Kuboki, Satoshi, Takada, Mamoru, Ohtsuka, Masayuki
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8228942/
https://ncbi.nlm.nih.gov/pubmed/34167573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-02019-0
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