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Procyanidin B2 Reduces Vascular Calcification through Inactivation of ERK1/2-RUNX2 Pathway

Vascular calcification is strongly associated with atherosclerotic plaque burden and plaque instability. The activation of extracellular signal-regulated kinase 1/2 (ERK1/2) increases runt related transcription factor 2 (RUNX2) expression to promote vascular calcification. Procyanidin B2 (PB2), a po...

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Vydáno v:Antioxidants (Basel)
Hlavní autoři: Liang, Yingquan, Chen, Guilan, Zhang, Feng, Yang, Xiaoxiao, Chen, Yuanli, Duan, Yajun, Yu, Maoyun, Zhang, Shuang, Han, Jihong
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8228429/
https://ncbi.nlm.nih.gov/pubmed/34198832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox10060916
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