Site-Specific Radiolabeling of a Human PD-L1 Nanobody via Maleimide–Cysteine Chemistry

Immune checkpoint inhibitors targeting the programmed cell death-1 (PD-1) and its ligand PD-L1 have proven to be efficient cancer therapies in a subset of patients. From all the patients with various cancer types, only 20% have a positive response. Being able to distinguish patients that do express...

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Bibliografiska uppgifter
I publikationen:Pharmaceuticals (Basel)
Huvudupphovsmän: Chigoho, Dora Mugoli, Lecocq, Quentin, Awad, Robin Maximilian, Breckpot, Karine, Devoogdt, Nick, Keyaerts, Marleen, Caveliers, Vicky, Xavier, Catarina, Bridoux, Jessica
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2021
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8228271/
https://ncbi.nlm.nih.gov/pubmed/34201323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14060550
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