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At-Line Reversed Phase Liquid Chromatography for In-Process Monitoring of Inclusion Body Solubilization
Refolding is known as the bottleneck in inclusion body (IB) downstream processing in the pharmaceutical industry: high dilutions leading to large operating volumes, slow refolding kinetics and low refolding yields are only a few of the problems that impede industrial application. Solubilization prio...
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| Publicado no: | Bioengineering (Basel) |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8228044/ https://ncbi.nlm.nih.gov/pubmed/34200471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/bioengineering8060078 |
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