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At-Line Reversed Phase Liquid Chromatography for In-Process Monitoring of Inclusion Body Solubilization

Refolding is known as the bottleneck in inclusion body (IB) downstream processing in the pharmaceutical industry: high dilutions leading to large operating volumes, slow refolding kinetics and low refolding yields are only a few of the problems that impede industrial application. Solubilization prio...

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Detaylı Bibliyografya
Yayımlandı:Bioengineering (Basel)
Asıl Yazarlar: Ebner, Julian, Humer, Diana, Klausser, Robert, Rubus, Viktor, Pell, Reinhard, Spadiut, Oliver, Kopp, Julian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8228044/
https://ncbi.nlm.nih.gov/pubmed/34200471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/bioengineering8060078
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