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Mitochondrial Caseinolytic Protease P: A Possible Novel Prognostic Marker and Therapeutic Target in Cancer

Caseinolytic protease P (ClpP) is a mitochondrial serine protease. In mammalian cells, the heterodimerization of ClpP and its AAA+ ClpX chaperone results in a complex called ClpXP, which has a relevant role in protein homeostasis and in maintaining mitochondrial functionality through the degradation...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Cormio, Antonella, Sanguedolce, Francesca, Pesce, Vito, Musicco, Clara
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8228031/
https://ncbi.nlm.nih.gov/pubmed/34207660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22126228
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