Human Keratinocytes Inhibit CD4(+) T-Cell Proliferation through TGFB1 Secretion and Surface Expression of HLA-G1 and PD-L1 Immune Checkpoints

Human skin protects the body against infection and injury. This protection involves immune and epithelial cells, but their interactions remain largely unknown. Here, we show that cultured epidermal keratinocytes inhibit allogenic CD4(+) T-cell proliferation under both normal and inflammatory conditi...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cells
Päätekijät: Mestrallet, Guillaume, Auvré, Frédéric, Schenowitz, Chantal, Carosella, Edgardo D., LeMaoult, Joel, Martin, Michèle T., Rouas-Freiss, Nathalie, Fortunel, Nicolas O.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2021
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8227977/
https://ncbi.nlm.nih.gov/pubmed/34201301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10061438
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