Human Keratinocytes Inhibit CD4(+) T-Cell Proliferation through TGFB1 Secretion and Surface Expression of HLA-G1 and PD-L1 Immune Checkpoints

Human skin protects the body against infection and injury. This protection involves immune and epithelial cells, but their interactions remain largely unknown. Here, we show that cultured epidermal keratinocytes inhibit allogenic CD4(+) T-cell proliferation under both normal and inflammatory conditi...

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Detaylı Bibliyografya
Yayımlandı:Cells
Asıl Yazarlar: Mestrallet, Guillaume, Auvré, Frédéric, Schenowitz, Chantal, Carosella, Edgardo D., LeMaoult, Joel, Martin, Michèle T., Rouas-Freiss, Nathalie, Fortunel, Nicolas O.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8227977/
https://ncbi.nlm.nih.gov/pubmed/34201301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10061438
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