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Oncogenic FGFR Fusions Produce Centrosome and Cilia Defects by Ectopic Signaling

A single primary cilium projects from most vertebrate cells to guide cell fate decisions. A growing list of signaling molecules is found to function through cilia and control ciliogenesis, including the fibroblast growth factor receptors (FGFR). Aberrant FGFR activity produces abnormal cilia with de...

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Bibliografske podrobnosti
izdano v:Cells
Main Authors: Nita, Alexandru, Abraham, Sara P., Krejci, Pavel, Bosakova, Michaela
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8227969/
https://ncbi.nlm.nih.gov/pubmed/34207779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10061445
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