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Cinnamic Acid Derivatives as Cardioprotective Agents against Oxidative and Structural Damage Induced by Doxorubicin

Doxorubicin (DOX) is a widely used anticancer drug. However, its clinical use is severely limited due to drug-induced cumulative cardiotoxicity, which leads to progressive cardiomyocyte dysfunction and heart failure. Enormous efforts have been made to identify potential strategies to alleviate DOX-i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Koczurkiewicz-Adamczyk, Paulina, Klaś, Katarzyna, Gunia-Krzyżak, Agnieszka, Piska, Kamil, Andrysiak, Kalina, Stępniewski, Jacek, Lasota, Sławomir, Wójcik-Pszczoła, Katarzyna, Dulak, Józef, Madeja, Zbigniew, Pękala, Elżbieta
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8227863/
https://ncbi.nlm.nih.gov/pubmed/34207549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22126217
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