Loss of Selenov predisposes mice to extra fat accumulation and attenuated energy expenditure

Selenoprotein V (SELENOV) is a new and the least conserved member of the selenoprotein family. Herein we generated Selenov knockout (KO) mice to determine its in vivo function. The KO led to 16–19% increases (P < 0.05) in body weight that were largely due to 54% higher (P < 0.05) fat mass accu...

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Vydáno v:Redox Biol
Hlavní autoři: Chen, Ling-Li, Huang, Jia-Qiang, Wu, Yuan-Yuan, Chen, Liang-Bing, Li, Shu-Ping, Zhang, Xu, Wu, Sen, Ren, Fa-Zheng, Lei, Xin-Gen
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2021
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8227834/
https://ncbi.nlm.nih.gov/pubmed/34167027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2021.102048
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