Feasibility of BRCA1/2 Testing of Formalin-Fixed and Paraffin-Embedded Pancreatic Tumor Samples: A Consecutive Clinical Series

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer, with most patients diagnosed at advanced stages. First-line treatment based on a combined chemotherapy (FOLFIRINOX or gemcitabine plus nab-paclitaxel) provides limited benefits. Olaparib, a PARP inhibitor, has been approved as maintena...

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Enregistré dans:
Détails bibliographiques
Publié dans:Diagnostics (Basel)
Auteurs principaux: Bruno, Rossella, Sensi, Elisa, Lupi, Cristiana, Giordano, Mirella, Bernardini, Laura, Vivaldi, Caterina, Fornaro, Lorenzo, Vasile, Enrico, Campani, Daniela, Fontanini, Gabriella
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8227758/
https://ncbi.nlm.nih.gov/pubmed/34200245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/diagnostics11061046
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