Role of 1q21 in Multiple Myeloma: From Pathogenesis to Possible Therapeutic Targets

Multiple myeloma (MM) is characterized by an accumulation of malignant plasma cells (PCs) in the bone marrow (BM). The amplification of 1q21 is one of the most common cytogenetic abnormalities occurring in around 40% of de novo patients and 70% of relapsed/refractory MM. Patients with this unfavorab...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Burroughs Garcìa, Jessica, Eufemiese, Rosa Alba, Storti, Paola, Sammarelli, Gabriella, Craviotto, Luisa, Todaro, Giannalisa, Toscani, Denise, Marchica, Valentina, Giuliani, Nicola
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8227721/
https://ncbi.nlm.nih.gov/pubmed/34205916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10061360
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