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Pharmacological Blockade of PPARα Exacerbates Inflammatory Pain-Related Impairment of Spatial Memory in Rats

Peroxisome proliferator-activated receptors (PPARs) are ligand-dependent transcription factors that exist in three isoforms: PPARα, PPARβ/δ and PPARγ. Studies suggest that the PPAR signalling system may modulate pain, anxiety and cognition. The aim of the present study was to investigate whether end...

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Detalhes bibliográficos
Publicado no:Biomedicines
Main Authors: Gaspar, Jessica C., Healy, Catherine, Ferdousi, Mehnaz I., Roche, Michelle, Finn, David P.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8227714/
https://ncbi.nlm.nih.gov/pubmed/34072060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9060610
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