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The Potential Roles of Blood–Brain Barrier and Blood–Cerebrospinal Fluid Barrier in Maintaining Brain Manganese Homeostasis

Manganese (Mn) is a trace nutrient necessary for life but becomes neurotoxic at high concentrations in the brain. The brain is a “privileged” organ that is separated from systemic blood circulation mainly by two barriers. Endothelial cells within the brain form tight junctions and act as the blood–b...

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Vydáno v:Nutrients
Hlavní autoři: McCabe, Shannon Morgan, Zhao, Ningning
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8227615/
https://ncbi.nlm.nih.gov/pubmed/34072120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu13061833
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