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Inhibiting Ferroptosis through Disrupting the NCOA4–FTH1 Interaction: A New Mechanism of Action

[Image: see text] Ferroptosis is an iron-dependent form of oxidative cell death, and the inhibition of ferroptosis is a promising strategy with which to prevent and treat neurological diseases. Herein we report a new ferroptosis inhibitor 9a with a novel mechanism of action. It is demonstrated that...

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Vydáno v:ACS Cent Sci
Hlavní autoři: Fang, Yuying, Chen, Xiucai, Tan, Qingyun, Zhou, Huihao, Xu, Jun, Gu, Qiong
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2021
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8227600/
https://ncbi.nlm.nih.gov/pubmed/34235259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.0c01592
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