Base-Resolution Analysis of Deoxyuridine at the Genome Scale Based on the Artificial Incorporation Modified Nucleobase

[Image: see text] Deamination of cytosine and dUMP misincorporation have been found to be capable of producing uracil in the genome. This study presents the AI-seq (artificial incorporation modified nucleobase for sequencing), a “base substitution”, which not only is capable of profiling uracil at s...

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Udgivet i:ACS Cent Sci
Main Authors: Wang, Yafen, Zhang, Xiong, Han, Shaoqing, Yang, Wei, Chen, Zonggui, Wu, Fan, Liu, Jizhou, Weng, Xiaocheng, Zhou, Xiang
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2021
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8227591/
https://ncbi.nlm.nih.gov/pubmed/34235258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.0c01504
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