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Application of Deep Neural Networks as a Prescreening Tool to Assign Individualized Absorption Models in Pharmacokinetic Analysis

A specific model for drug absorption is necessarily assumed in pharmacokinetic (PK) analyses following extravascular dosing. Unfortunately, an inappropriate absorption model may force other model parameters to be poorly estimated. An added complexity arises in population PK analyses when different i...

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Bibliographic Details
Published in:Pharmaceutics
Main Authors: Jaber, Mutaz M., Yaman, Burhaneddin, Sarafoglou, Kyriakie, Brundage, Richard C.
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8227048/
https://ncbi.nlm.nih.gov/pubmed/34073609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13060797
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