Inhibition of Hsp90 Counteracts the Established Experimental Dermal Fibrosis Induced by Bleomycin

Our previous study demonstrated that heat shock protein 90 (Hsp90) is overexpressed in the involved skin of patients with systemic sclerosis (SSc) and in experimental dermal fibrosis. Pharmacological inhibition of Hsp90 prevented the stimulatory effects of transforming growth factor-beta on collagen...

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Detalhes bibliográficos
Publicado no:Biomedicines
Main Authors: Štorkánová, Hana, Štorkánová, Lenka, Navrátilová, Adéla, Bečvář, Viktor, Hulejová, Hana, Oreská, Sabína, Heřmánková, Barbora, Špiritović, Maja, Bečvář, Radim, Pavelka, Karel, Vencovský, Jiří, Distler, Jörg H. W., Šenolt, Ladislav, Tomčík, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8226767/
https://ncbi.nlm.nih.gov/pubmed/34200311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9060650
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