In Vitro Evaluation of the Squaramide-Conjugated Fibroblast Activation Protein Inhibitor-Based Agents AAZTA(5).SA.FAPi and DOTA.SA.FAPi

Recently, the first squaramide-(SA) containing FAP inhibitor-derived radiotracers were introduced. DATA(5m).SA.FAPi and DOTA.SA.FAPi with their non-radioactive complexes showed high affinity and selectivity for FAP. After a successful preclinical study with [(68)Ga]Ga-DOTA.SA.FAPi, the first patient...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Moon, Euy Sung, Van Rymenant, Yentl, Battan, Sandeep, De Loose, Joni, Bracke, An, Van der Veken, Pieter, De Meester, Ingrid, Rösch, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8226449/
https://ncbi.nlm.nih.gov/pubmed/34201111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26123482
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