Porcine RIG-I and MDA5 Signaling CARD Domains Exert Similar Antiviral Function Against Different Viruses

The RIG-I-like receptors (RLRs) RIG-I and MDA5 play critical roles in sensing and fighting viral infections. Although RIG-I and MDA5 have similar molecular structures, these two receptors have distinct features during activation. Further, the signaling domains of the N terminal CARD domains (CARDs)...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Microbiol
Prif Awduron: Li, Shuangjie, Shao, Qi, Zhu, Yuanyuan, Ji, Xingyu, Luo, Jia, Xu, Yulin, Liu, Xueliang, Zheng, Wanglong, Chen, Nanhua, Meurens, François, Zhu, Jianzhong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2021
Pynciau:
Microbiology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8226225/
https://ncbi.nlm.nih.gov/pubmed/34177861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2021.677634
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