Polydatin Reduces Cardiotoxicity and Enhances the Anticancer Effects of Sunitinib by Decreasing Pro-Oxidative Stress, Pro-Inflammatory Cytokines, and NLRP3 Inflammasome Expression

Renal cell carcinoma (RCC) represents the main renal tumors and are highly metastatic. Sunitinib, a recently-approved, multi-targeted Tyrosine Kinases Inhibitor (TKi), prolongs survival in patients with metastatic renal cell carcinoma and gastrointestinal stromal tumors, however a dose related cardi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Oncol
Egile Nagusiak: Quagliariello, Vincenzo, Berretta, Massimiliano, Buccolo, Simona, Iovine, Martina, Paccone, Andrea, Cavalcanti, Ernesta, Taibi, Rosaria, Montopoli, Monica, Botti, Gerardo, Maurea, Nicola
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2021
Gaiak:
Oncology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8226180/
https://ncbi.nlm.nih.gov/pubmed/34178667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.680758
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