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Targeting the MYC Ubiquitination-Proteasome Degradation Pathway for Cancer Therapy
Deregulated MYC overexpression and activation contributes to tumor growth and progression. Given the short half-life and unstable nature of the MYC protein, it is not surprising that the oncoprotein is highly regulated via diverse posttranslational mechanisms. Among them, ubiquitination dynamically...
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| Pubblicato in: | Front Oncol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8226175/ https://ncbi.nlm.nih.gov/pubmed/34178666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.679445 |
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