Combining inhibitors of Brd4 and cyclin-dependent kinase can decrease tumor growth in neuroblastoma with MYCN amplification

INTRODUCTION: High-risk neuroblastoma is a deadly disease; poor prognosticators are MYCN-amplification and TERT-overexpression. We hypothesized that Gene Set Enrichment Analysis (GSEA) could identify pathways associated with MYCN-amplification and that inhibition of these pathways could decrease tum...

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Detaylı Bibliyografya
Yayımlandı:J Pediatr Surg
Asıl Yazarlar: Wood, Lauren, Huang, Min, Zeki, Jasmine, Gong, Miao, Taylor, Jordan, Shimada, Hiroyuki, Chiu, Bill
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8225564/
https://ncbi.nlm.nih.gov/pubmed/33838899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpedsurg.2021.03.037
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