Molecular Level Characterization of Circulating Aquaporin-4 Antibodies in Neuromyelitis Optica Spectrum Disorder

OBJECTIVE: To determine whether distinct aquaporin-4 (AQP4)-IgG lineages play a role in neuromyelitis optica spectrum disorder (NMOSD) pathogenesis, we profiled the AQP4-IgG polyclonal serum repertoire and identified, quantified, and functionally characterized distinct AQP4-IgG lineages circulating...

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Dades bibliogràfiques
Publicat a:Neurol Neuroimmunol Neuroinflamm
Autors principals: Li, Jie, Bazzi, Sam A., Schmitz, Florian, Tanno, Hidetaka, McDaniel, Jonathan R., Lee, Chang-Han, Joshi, Chaitanya, Kim, Jin Eyun, Monson, Nancy, Greenberg, Benjamin M., Hedfalk, Kristina, Melamed, Esther, Ippolito, Gregory C.
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8225010/
https://ncbi.nlm.nih.gov/pubmed/34168058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000001034
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