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Persistence of Coxsackievirus B4 in Pancreatic β Cells Disturbs Insulin Maturation, Pattern of Cellular Proteins, and DNA Methylation

Coxsackievirus-B4 (CV-B4) can persist in pancreatic cell lines and impair the phenoytpe and/or gene expressions in these cells; however, the models used to study this phenomenon did not produce insulin. Therefore, we investigated CV-B4 persistence and its consequences in insulin-producing pancreatic...

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Publicado en:Microorganisms
Autores principales: Nekoua, Magloire Pandoua, Bertin, Antoine, Sane, Famara, Gimeno, Jean-Pascal, Fournier, Isabelle, Salzet, Michel, Engelmann, Ilka, Alidjinou, Enagnon Kazali, Hober, Didier
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8224704/
https://ncbi.nlm.nih.gov/pubmed/34067388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/microorganisms9061125
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