Inhibitory Effects of Epipolythiodioxopiperazine Fungal Metabolites on Isocitrate Lyase in the Glyoxylate Cycle of Candida albicans

Four epipolythiodioxopiperazine fungal metabolites (1–4) isolated from the sponge-derived Aspergillus quadrilineatus FJJ093 were evaluated for their capacity to inhibit isocitrate lyase (ICL) in the glyoxylate cycle of Candida albicans. The structures of these compounds were elucidated using spectro...

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Bibliografiske detaljer
Udgivet i:Mar Drugs
Main Authors: Hwang, Ji-Yeon, Chung, Beomkoo, Kwon, Oh-Seok, Park, Sung Chul, Cho, Eunji, Oh, Dong-Chan, Shin, Jongheon, Oh, Ki-Bong
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8224697/
https://ncbi.nlm.nih.gov/pubmed/34067454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md19060295
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