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Rap1a Regulates Cardiac Fibroblast Contraction of 3D Diabetic Collagen Matrices by Increased Activation of the AGE/RAGE Cascade

Cardiovascular disease is a common diabetic complication that can arise when cardiac fibroblasts transition into myofibroblasts. Myofibroblast transition can be induced by advanced glycated end products (AGEs) present in the extracellular matrix (ECM) activating RAGE (receptor for advanced glycated...

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Vydáno v:Cells
Hlavní autoři: Burr, Stephanie D., Stewart, James A.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8224555/
https://ncbi.nlm.nih.gov/pubmed/34067282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10061286
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