Proteomic Analysis of Rhesus Macaque Brain Explants Treated With Borrelia burgdorferi Identifies Host GAP-43 as a Potential Factor Associated With Lyme Neuroborreliosis

BACKGROUND: Lyme neuroborreliosis (LNB) is one of the most dangerous manifestations of Lyme disease, but the pathogenesis and inflammatory mechanisms are not fully understood. METHODS: Cultured explants from the frontal cortex of rhesus monkey brain (n=3) were treated with live Borrelia burgdorferi...

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Detalles Bibliográficos
Publicado en:Front Cell Infect Microbiol
Main Authors: Li, Lianbao, Luo, Lisha, Chen, Taigui, Cao, Wenjing, Xu, Xin, Zhang, Yu, Yue, Peng, Fan, Yuxin, Chen, Jingjing, Liu, Meixiao, Ma, Mingbiao, Tao, Lvyan, Peng, Yun, Dong, Yan, Li, Bingxue, Luo, Suyi, Kong, Jing, Zhou, Guozhong, Wen, Shiyuan, Liu, Aihua, Bao, Fukai
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Cellular and Infection Microbiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8224226/
https://ncbi.nlm.nih.gov/pubmed/34178719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2021.647662
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