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Targeting nectin-4 by antibody-drug conjugates for the treatment of urothelial carcinoma

INTRODUCTION: Nectin-4 is a tumor-associated antigen overexpressed in urothelial carcinoma and several other malignancies. It has emerged as a compelling target for novel tumor-directed therapies, particularly as a component of antibody-drug conjugates (ADCs), a growing class of anti-cancer therapeu...

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Detalhes bibliográficos
Publicado no:Expert Opin Biol Ther
Main Authors: Wong, Jeffrey L., Rosenberg, Jonathan E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8224177/
https://ncbi.nlm.nih.gov/pubmed/34030536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14712598.2021.1929168
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